SLC1A4

Protein name: ASCT1, SATT Aliases: System ASC Substrates: L-Ala, L-Ser, L-Cys, L-Thr Transport type: Cotransporter / Na+, E / amino acids Tissue and cellular expression: widespread Subcellular expression: N/D Disease: N/D Locus: 2p15-p13 Sequence ID: NP_001180422.1, NM_001193493.1 NP_003029.2, NM_003038.4 Gene ID: 6509 Splice variants: 2 splice variants differ in their 5' UTR, coding sequences, start codon

SATT_HUMAN (UniProt)

Gene names: SLC1A4, ASCT1, SATT
Protein names and data: SATT_HUMAN, Full=Neutral amino acid transporter A, Full=Alanine/serine/cysteine/threonine transporter 1;Short=ASCT-1;Full=SATT;Full=Solute carrier family 1 member 4; Length: 532 a.a., Mass: 55723 Da,
fasta formatted sequence

Function: Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence
Cellular location: Membrane; Multi-pass membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Tissue specificity: Expressed mostly in brain, muscle, and pancreas but detected in all tissues examined

Database cross-references

UniProt: P43007
NextBio: 25311
OMIM: 600229
Ensembl: ENST00000531327
GeneCard: GC02P064949
TCDB: 2.A.23.3.1
PharmGenUCSF: SLC1A4
Guide to Pharmacology: SLC1A4 (873)
Alanine/serine/cysteine transporter subfamily (873)

HGNC: HGNC:10942

Genetic variants

See also Ensembl:ENST00000531327